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High affinity threading of a new tetralactam macrocycle in water by fluorescent deep-red and near-infrared squaraine dyes.

ABSTRACT: A new tetralactam macrocycle was prepared and found to encapsulate deep-red and near-infrared squaraine and croconaine dyes in water with tunable threading kinetics. The new supramolecular paradigm of guest back-folding was used to increase macrocycle/squaraine affinity by 370-fold and achieve an association constant of 2.8 × 109 M-1.

SUBMITTER: Dempsey JM

PROVIDER: S-EPMC6827183 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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High affinity threading of a new tetralactam macrocycle in water by fluorescent deep-red and near-infrared squaraine dyes.

Dempsey Janel M JM Zhai Canjia C McGarraugh Hannah H HH Schreiber Cynthia L CL Stoffel Shannon E SE Johnson Andrew A Smith Bradley D BD

Chemical communications (Cambridge, England) 20191008 85

A new tetralactam macrocycle was prepared and found to encapsulate deep-red and near-infrared squaraine and croconaine dyes in water with tunable threading kinetics. The new supramolecular paradigm of guest back-folding was used to increase macrocycle/squaraine affinity by 370-fold and achieve an association constant of 2.8 × 10<sup>9</sup> M<sup>-1</sup>. ...[more]

PMID: 31593200

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