Cupredoxins--a study of how proteins may evolve to use metals for bioenergetic processes.
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ABSTRACT:
SUBMITTER: Choi M
PROVIDER: S-EPMC6916721 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Publications
Cupredoxins--a study of how proteins may evolve to use metals for bioenergetic processes.
Choi Moonsung M Davidson Victor L VL
Metallomics : integrated biometal science 20110124 2
Cupredoxins are small proteins that contain type I copper centers, which are ubiquitous in nature. They function as electron transfer shuttles between proteins. This review of the structure and properties of native cupredoxins, and those modified by site-directed mutagenesis, illustrates how these proteins may have evolved to specifically bind copper, develop recognition sites for specific redox partners, tune redox potential for a particular function, and allow for efficient electron transfer t ...[more]
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