Ontology highlight
ABSTRACT:
SUBMITTER: Zhang JQ
PROVIDER: S-EPMC7041248 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Genome biology 20200224 1
Single-cell RNA sequencing has emerged as a powerful tool for characterizing cells, but not all phenotypes of interest can be observed through changes in gene expression. Linking sequencing with optical analysis has provided insight into the molecular basis of cellular function, but current approaches have limited throughput. Here, we present a high-throughput platform for linked optical and gene expression profiling of single cells. We demonstrate accurate fluorescence and gene expression measu ...[more]