Ontology highlight
ABSTRACT:
SUBMITTER: Manton JD
PROVIDER: S-EPMC7173891 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Biomedical optics express 20200320 4
Wide-field fluorescence microscopy, while much faster than confocal microscopy, suffers from a lack of optical sectioning and poor axial resolution. 3D structured illumination microscopy (SIM) has been demonstrated to provide optical sectioning and to double the resolution limit both laterally and axially, but even with this the axial resolution is still worse than the lateral resolution of unmodified wide-field microscopy. Interferometric schemes using two high numerical aperture objectives, su ...[more]