Ontology highlight
ABSTRACT:
SUBMITTER: Marianski M
PROVIDER: S-EPMC7187407 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20200302 15
The stereoselective formation of 1,2-cis-glycosidic bonds is challenging. However, 1,2-cis-selectivity can be induced by remote participation of C4 or C6 ester groups. Reactions involving remote participation are believed to proceed via a key ionic intermediate, the glycosyl cation. Although mechanistic pathways were postulated many years ago, the structure of the reaction intermediates remained elusive owing to their short-lived nature. Herein, we unravel the structure of glycosyl cations invol ...[more]