Ontology highlight
ABSTRACT:
SUBMITTER: Boddapati SNM
PROVIDER: S-EPMC7221555 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20200414 8
A facile, one-pot, and proficient method was developed for the production of various 2-arylaminobenzimidazoles. This methodology is based for the first time on a copper catalyst promoted domino C-N cross-coupling reaction for the generation of 2-arylaminobenzimidazoles. Mechanistic investigations revealed that the synthetic pathway involves a copper-based desulphurization/nucleophilic substitution and a subsequent domino intra and intermolecular C-N cross-coupling reactions. Some of the issues t ...[more]