Ontology highlight
ABSTRACT:
SUBMITTER: Caussy C
PROVIDER: S-EPMC7257854 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Caussy Cyrielle C Chuang Jen-Chieh JC Billin Andrew A Hu Tao T Wang Ya Y Subramanian G Mani GM Djedjos C Stephen CS Myers Robert P RP Dennis Edward A EA Loomba Rohit R
Therapeutic advances in gastroenterology 20200526
<h4>Background</h4>Eicosanoid and related docosanoid polyunsaturated fatty acids (PUFAs) and their oxygenated derivatives have been proposed as noninvasive lipidomic biomarkers of nonalcoholic steatohepatitis (NASH). Therefore, we investigated associations between plasma eicosanoids and liver fibrosis to evaluate their utility in diagnosing and monitoring NASH-related fibrosis.<h4>Methods</h4>Our analysis used baseline eicosanoid data from 427 patients with biopsy-confirmed nonalcoholic fatty li ...[more]