Ontology highlight
ABSTRACT:
SUBMITTER: Adderley JD
PROVIDER: S-EPMC7419518 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Adderley Jack D JD John von Freyend Simona S Jackson Sarah A SA Bird Megan J MJ Burns Amy L AL Anar Burcu B Metcalf Tom T Semblat Jean-Philippe JP Billker Oliver O Wilson Danny W DW Doerig Christian C
Nature communications 20200811 1
Intracellular pathogens mobilize host signaling pathways of their host cell to promote their own survival. Evidence is emerging that signal transduction elements are activated in a-nucleated erythrocytes in response to infection with malaria parasites, but the extent of this phenomenon remains unknown. Here, we fill this knowledge gap through a comprehensive and dynamic assessment of host erythrocyte signaling during infection with Plasmodium falciparum. We used arrays of 878 antibodies directed ...[more]