Ontology highlight
ABSTRACT:
SUBMITTER: Pinkard O
PROVIDER: S-EPMC7428014 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Nature communications 20200814 1
Transfer RNAs (tRNA) are quintessential in deciphering the genetic code; disseminating nucleic acid triplets into correct amino acid identity. While this decoding function is clear, an emerging theme is that tRNA abundance and functionality can powerfully impact protein production rate, folding, activity, and messenger RNA stability. Importantly, however, the expression pattern of tRNAs is obliquely known. Here we present Quantitative Mature tRNA sequencing (QuantM-tRNA seq), a technique to moni ...[more]