In vivo testing of the low-flow CO₂ removal application of a compact, platform respiratory device.

ABSTRACT:

Background

Non-invasive and lung-protective ventilation techniques may improve outcomes for patients with an acute exacerbation of chronic obstructive pulmonary disease or moderate acute respiratory distress syndrome by reducing airway pressures. These less invasive techniques can fail due to hypercapnia and require transitioning patients to invasive mechanical ventilation. Extracorporeal CO₂ removal devices remove CO₂ independent of the lungs thereby controlling the hypercapnia and permitting non-invasive or lung-protective ventilation techniques. We are developing the Modular Extracorporeal Lung Assist System as a platform technology capable of providing three levels of respiratory assist: adult and pediatric full respiratory support and adult low-flow CO

SUBMITTER: May AG 

PROVIDER: S-EPMC7429452 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature