Ontology highlight
ABSTRACT:
SUBMITTER: Pintilie G
PROVIDER: S-EPMC7446556 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Nature methods 20200210 3
Cryogenic electron microscopy (cryo-EM) maps are now at the point where resolvability of individual atoms can be achieved. However, resolvability is not necessarily uniform throughout the map. We introduce a quantitative parameter to characterize the resolvability of individual atoms in cryo-EM maps, the map Q-score. Q-scores can be calculated for atoms in proteins, nucleic acids, water, ligands and other solvent atoms, using models fitted to or derived from cryo-EM maps. Q-scores can also be av ...[more]