Ontology highlight
ABSTRACT:
SUBMITTER: Mateos-Aparicio P
PROVIDER: S-EPMC7479826 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Mateos-Aparicio Pedro P Bello Sabina A SA Rodríguez-Moreno Antonio A
Frontiers in cell and developmental biology 20200826
Neurons derived from human induced pluripotent stem cells (hiPSC-derived neurons) offer novel opportunities for the development of preclinical models of human neurodegenerative diseases (NDDs). Recent advances in the past few years have increased substantially the potential of these techniques and have uncovered new challenges that the field is facing. Here, we outline and discuss challenges related to the functional characterization of hiPSC-derived neurons and propose ways to overcome current ...[more]