Ontology highlight
ABSTRACT:
SUBMITTER: Cottrell CA
PROVIDER: S-EPMC7485981 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
PLoS pathogens 20200831 8
The induction of broad and potent immunity by vaccines is the key focus of research efforts aimed at protecting against HIV-1 infection. Soluble native-like HIV-1 envelope glycoproteins have shown promise as vaccine candidates as they can induce potent autologous neutralizing responses in rabbits and non-human primates. In this study, monoclonal antibodies were isolated and characterized from rhesus macaques immunized with the BG505 SOSIP.664 trimer to better understand vaccine-induced antibody ...[more]