Ontology highlight
ABSTRACT:
SUBMITTER: Chen C
PROVIDER: S-EPMC7535930 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Chen Cuie C Yamashita Yukiko M YM
eLife 20200923
Asymmetrically dividing stem cells often show asymmetric behavior of the mother versus daughter centrosomes, whereby the self-renewing stem cell selectively inherits the mother or daughter centrosome. Although the asymmetric centrosome behavior is widely conserved, its biological significance remains largely unclear. Here, we show that Alms1a, a <i>Drosophila</i> homolog of the human ciliopathy gene Alstrom syndrome, is enriched on the mother centrosome in <i>Drosophila</i> male germline stem ce ...[more]