Master regulator genes and their impact on major diseases.
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ABSTRACT:
SUBMITTER: Cai W
PROVIDER: S-EPMC7546222 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Master regulator genes and their impact on major diseases.
Cai Wanwan W Zhou Wanbang W Han Zhe Z Lei Junrong J Zhuang Jian J Zhu Ping P Wu Xiushan X Yuan Wuzhou W
PeerJ 20201006
Master regulator genes (MRGs) have become a hot topic in recent decades. They not only affect the development of tissue and organ systems but also play a role in other signal pathways by regulating additional MRGs. Because a MRG can regulate the concurrent expression of several genes, its mutation often leads to major diseases. Moreover, the occurrence of many tumors and cardiovascular and nervous system diseases are closely related to MRG changes. With the development in omics technology, an in ...[more]
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