Ontology highlight
ABSTRACT:
SUBMITTER: Pizzolitto C
PROVIDER: S-EPMC7554727 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Pizzolitto Chiara C Cok Michela M Asaro Fioretta F Scognamiglio Francesca F Marsich Eleonora E Lopez Francesco F Donati Ivan I Sacco Pasquale P
International journal of molecular sciences 20200917 18
The present manuscript deals with the elucidation of the mechanism of genipin binding by primary amines at neutral pH. UV-VIS and CD measurements both in the presence of oxygen and in oxygen-depleted conditions, combined with computational analyses, led to propose a novel mechanism for the formation of genipin derivatives. The indications collected with chiral and achiral primary amines allowed interpreting the genipin binding to a lactose-modified chitosan (CTL or Chitlac), which is soluble at ...[more]