Ontology highlight
ABSTRACT:
SUBMITTER: Ohnishi K
PROVIDER: S-EPMC7596061 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Ohnishi Kohei K Saito Shigeru S Miura Toru T Ohta Akane A Tominaga Makoto M Sokabe Takaaki T Kuhara Atsushi A
Scientific reports 20201029 1
Caenorhabditis elegans (C. elegans) exhibits cold tolerance and temperature acclimatisation regulated by a small number of head sensory neurons, such as the ADL temperature-sensing neurons that express three transient receptor potential vanilloid (TRPV) channel subunits, OSM-9, OCR-2, and OCR-1. Here, we show that an OSM-9/OCR-2 regulates temperature acclimatisation and acts as an accessorial warmth-sensing receptor in ADL neurons. Caenorhabditis elegans TRPV channel mutants showed abnormal temp ...[more]