Ontology highlight
ABSTRACT:
SUBMITTER: Focaroli S
PROVIDER: S-EPMC7699582 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Focaroli Stefano S Jiang Guannan G O'Connell Peter P Fahy John V JV Healy Anne-Marie AM
Pharmaceutics 20201120 11
The aim of this study was to investigate the use of a three-fluid atomising nozzle in a lab-scale spray dryer for the production of dry powders intended for pulmonary delivery. Powders were composed of salbutamol sulphate and theophylline in different weight ratios. The three-fluid nozzle technology enabled powders containing a high theophylline content to be obtained, overcoming the problems associated with its relatively low solubility, by pumping two separate feed solutions (containing the tw ...[more]