Ontology highlight
ABSTRACT:
SUBMITTER: Park SR
PROVIDER: S-EPMC7710921 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Structure (London, England : 1993) 20200806 12
Single-molecule detection and manipulation is a powerful tool for unraveling dynamic biological processes. Unfortunately, success in such experiments is often challenged by tethering the biomolecule(s) of interest to a biocompatible surface. Here, we describe a robust surface passivation method by dense polymer brush grafting, based on optimized polyethylene glycol (PEG) deposition conditions, exactly at the lower critical point of an aqueous biphasic PEG-salt system. The increased biocompatibil ...[more]