Ontology highlight
ABSTRACT:
SUBMITTER: Taubert S
PROVIDER: S-EPMC7754328 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Täubert Sebastian S Zhang Yong-Hui YH Martinez Mitcheell Maestre MM Siepel Florian F Wöltjen Edith E Leonov Andrei A Griesinger Christian C
Chembiochem : a European journal of chemical biology 20200817 23
Although lanthanide tags, which have large anisotropic magnetic susceptibilities, have already been introduced to enrich NMR parameters by long-range pseudoconact shifts (PCSs) and residual dipolar couplings (RDCs) of proteins, their application to nucleotides has so far been limited to one previous report, due to the high affinities of lanthanides for the phosphodiester backbone of nucleotides and difficult organic synthesis. Herein, we report successful attachment of a lanthanide tag to a chem ...[more]