Ontology highlight
ABSTRACT:
SUBMITTER: Spiliotis ET
PROVIDER: S-EPMC7851956 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Spiliotis Elias T ET McMurray Michael A MA
Molecular biology of the cell 20201001 21
Septins are a unique family of GTPases, which were discovered 50 years ago as essential genes for the asymmetric cell shape and division of budding yeast. Septins assemble into filamentous nonpolar polymers, which associate with distinct membrane macrodomains and subpopulations of actin filaments and microtubules. While structurally a cytoskeleton-like element, septins function predominantly as spatial regulators of protein localization and interactions. Septin scaffolds and barriers have provid ...[more]