Ontology highlight
ABSTRACT:
SUBMITTER: Yeh JY
PROVIDER: S-EPMC7940356 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Yeh Jia-Yin JY Lin Hwai-Jeng HJ Kuo Chia-Jung CJ Feng Chun-Lung CL Chou Chia-Huei CH Lin Chia-Der CD Wu Hui-Yu HY Li Chen-Yi CY Chiu Cheng-Hsun CH Lai Chih-Ho CH
Frontiers in cell and developmental biology 20210223
<i>Helicobacter pylori</i> infection is associated with several gastrointestinal diseases, including gastritis, peptic ulcer, and gastrointestinal adenocarcinoma. Two major cytotoxins, vacuolating cytotoxin A (VacA) and cytotoxin-associated gene A (CagA), interact closely with lipid rafts, contributing to <i>H. pylori</i>-associated disease progression. The <i>Campylobacter jejuni</i> cytolethal distending toxin consists of three subunits: CdtA, CdtB, and CdtC. Among them, CdtA and CdtC bind to ...[more]