Ontology highlight
ABSTRACT:
SUBMITTER: Borocci S
PROVIDER: S-EPMC8196891 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Borocci Stefano S Cerchia Carmen C Grottesi Alessandro A Sanna Nico N Prandi Ingrid Guarnetti IG Abid Nabil N Beccari Andrea R AR Chillemi Giovanni G Talarico Carmine C
International journal of molecular sciences 20210522 11
The COVID-19 pandemic is caused by SARS-CoV-2. Currently, most of the research efforts towards the development of vaccines and antibodies against SARS-CoV-2 were mainly focused on the spike (S) protein, which mediates virus entry into the host cell by binding to ACE2. As the virus SARS-CoV-2 continues to spread globally, variants have emerged, characterized by multiple mutations of the S glycoprotein. Herein, we employed microsecond-long molecular dynamics simulations to study the impact of the ...[more]