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Drug-drug cocrystals: Opportunities and challenges.


ABSTRACT: Recently, drug-drug cocrystal attracts more and more attention. It offers a low risk, low-cost but high reward route to new and better medicines and could improve the physiochemical and biopharmaceutical properties of a medicine by addition of a suitable therapeutically effective component without any chemical modification. Having so many advantages, to date, the reported drug-drug cocrystals are rare. Here we review the drug-drug cocrystals that reported in last decade and shed light on the opportunities and challenges for the development of drug-drug cocrystals.

SUBMITTER: Wang X 

PROVIDER: S-EPMC8261079 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

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Drug-drug cocrystals: Opportunities and challenges.

Wang Xiaojuan X   Du Shuzhang S   Zhang Rui R   Jia Xuedong X   Yang Ting T   Zhang Xiaojian X  

Asian journal of pharmaceutical sciences 20200709 3


Recently, drug-drug cocrystal attracts more and more attention. It offers a low risk, low-cost but high reward route to new and better medicines and could improve the physiochemical and biopharmaceutical properties of a medicine by addition of a suitable therapeutically effective component without any chemical modification. Having so many advantages, to date, the reported drug-drug cocrystals are rare. Here we review the drug-drug cocrystals that reported in last decade and shed light on the opp  ...[more]

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