A magneto-optical biochip for rapid assay based on the Cotton-Mouton effect of γ-Fe₂O₃@Au core/shell nanoparticles.

ABSTRACT:

Background

In the past decades, different diseases and viruses, such as Ebola, MERS and COVID-19, impacted the human society and caused huge cost in different fields. With the increasing threat from the new or unknown diseases, the demand of rapid and sensitive assay method is more and more urgent.

Results

In this work, we developed a magneto-optical biochip based on the Cotton-Mouton effect of γ-Fe₂O₃@Au core/shell magnetic nanoparticles. We performed a proof-of-concept experiment for the detection of the spike glycoprotein S of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The assay was achieved by measuring the magneto-optical Cotton-Mouton effect of the biochip. This magneto-optical biochip can not only be used to detect SARS-CoV-2 b

SUBMITTER: Chen KL 

PROVIDER: S-EPMC8485105 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature