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Electrooxidative o-carborane chalcogenations without directing groups: cage activation by copper catalysis at room temperature† † Electronic supplementary information (ESI) available. CCDC 2049567 (3aa), 2049566 (3am), 2049564 (3ao), 2065339 (4br), 2049565 (4av) and 2063919 (5b). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/d1sc02905c

ABSTRACT: Copper-catalyzed electrochemical direct chalcogenations of o-carboranes was established at room temperature. Thereby, a series of cage C-sulfenylated and C-selenylated o-carboranes anchored with valuable functional groups was accessed with high levels of position- and chemo-selectivity control. The cupraelectrocatalysis provided efficient means to activate otherwise inert cage C–H bonds for the late-stage diversification of o-carboranes. Copper-catalyzed electrochemical cage C–H chalcogenation of o-carboranes has been realized to enable the synthesis of various cage C-sulfenylated and C-selenylated o-carboranes.

SUBMITTER: Yang L

PROVIDER: S-EPMC8513870 | biostudies-literature |

REPOSITORIES: biostudies-literature

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