A perception-based nanosensor platform to detect cancer biomarkers.
Ontology highlight
ABSTRACT:
SUBMITTER: Yaari Z
PROVIDER: S-EPMC8604403 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Publications
A perception-based nanosensor platform to detect cancer biomarkers.
Yaari Zvi Z Yang Yoona Y Apfelbaum Elana E Cupo Christian C Settle Alex H AH Cullen Quinlan Q Cai Winson W Long Roche Kara K Levine Douglas A DA Fleisher Martin M Ramanathan Lakshmi L Zheng Ming M Jagota Anand A Heller Daniel A DA
Science advances 20211119 47
Conventional molecular recognition elements, such as antibodies, present issues for developing biomolecular assays for use in certain technologies, such as implantable devices. Additionally, antibody development and use, especially for highly multiplexed applications, can be slow and costly. We developed a perception-based platform based on an optical nanosensor array that leverages machine learning algorithms to detect multiple protein biomarkers in biofluids. We demonstrated this platform in g ...[more]
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