Ontology highlight
ABSTRACT:
SUBMITTER: Balachandran H
PROVIDER: S-EPMC8768427 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Balachandran Harikrishnan H Phetsouphanh Chansavath C Agapiou David D Adhikari Anurag A Rodrigo Chaturaka C Hammoud Mohamed M Shrestha Lok Bahadur LB Keoshkerian Elizabeth E Gupta Money M Turville Stuart S Christ Daniel D King Cecile C Sasson Sarah C SC Bartlett Adam A Grubor-Bauk Branka B Rawlinson William W Aggarwal Anupriya A Stella Alberto Ospina AO Klemm Vera V Mina Michael M MM Post Jeffrey J JJ Hudson Bernard B Gilroy Nicky N Konecny Pam P Ahlenstiel Golo G Dwyer Dominic E DE Sorrell Tania C TC Kelleher Anthony A Tedla Nicodemus N Lloyd Andrew R AR Martinello Marianne M Bull Rowena A RA
Cell reports 20220119 6
Understanding the long-term maintenance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity is critical for predicting protection against reinfection. In an age- and gender-matched cohort of 24 participants, the association of disease severity and early immune responses on the maintenance of humoral immunity 12 months post-infection is examined. All severely affected participants maintain a stable subset of SARS-CoV-2 receptor-binding domain (RBD)-specific memory B cells (MB ...[more]