Ontology highlight
ABSTRACT:
SUBMITTER: Ma X
PROVIDER: S-EPMC8787451 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Ma Xiaojian X Tan Xi X Yu Bingbing B Sun Wanwei W Wang Heping H Hu Huijun H Du Yanyun Y He Ruirui R Gao Ru R Peng Qianwen Q Cui Zhihui Z Pan Ting T Feng Xiong X Wang Junhan J Xu Chengqi C Zhu Bin B Liu Wei W Wang Chenhui C
Cellular & molecular immunology 20220125 5
Fungal infections cause ~1.5 million deaths each year worldwide, and the mortality rate of disseminated candidiasis currently exceeds that of breast cancer and malaria. The major reasons for the high mortality of candidiasis are the limited number of antifungal drugs and the emergence of drug-resistant species. Therefore, a better understanding of antifungal host defense mechanisms is crucial for the development of effective preventive and therapeutic strategies. Here, we report that DOCK2 (dedi ...[more]