Ontology highlight
ABSTRACT:
SUBMITTER: Jin H
PROVIDER: S-EPMC8894365 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Jin Heejin H Yoo Hyun Ju HJ Kim Ye An YA Lee Ji Hyun JH Lee Young Y Kwon Seung-Hyun SH Seo Young Joo YJ Lee Seung Hun SH Koh Jung-Min JM Ji Yunmi Y Do Ah Ra AR Won Sungho S Seo Je Hyun JH
Scientific reports 20220303 1
Sarcopenia is an age-related disorder characterised by a progressive decrease in skeletal muscle mass. As the genetic biomarkers for sarcopenia are not yet well characterised, this study aimed to investigate the genetic variations related to sarcopenia in a relatively aged cohort, using genome-wide association study (GWAS) meta-analyses of lean body mass (LBM) in 6961 subjects. Two Korean cohorts were analysed, and subgroup GWAS was conducted for appendicular skeletal muscle mass (ASM) and skele ...[more]