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A curcumin-based AIEE-active fluorescent probe for Cu²⁺ detection in aqueous solution.

ABSTRACT: Curcuminoids have been extensively investigated as metal ion probes, but the intrinsic aggregation-caused-quenching (ACQ) characteristic of curcumin would hinder their applications in aqueous solution. Fortunately, tetraphenylethylene (TPE) could endow the compounds with aggregation-induced emission (AIE)/aggregation-induced enhanced emission (AIEE) characteristics to eliminate the ACQ effect. According to this strategy, a series of TPE-modified curcumin derivatives L1-4 were prepared and studied for their AIEE properties. Among the four TPE-curcumin analogues, only L1 particles have been successfully used as an on-off fluorescence probe for detecting Cu²⁺ in aqueous solution. The fluorescence titration experiment determined its detection limit of 1.49 × 10^-7 mol L^-1, and the binding ratio between L1 and Cu²⁺ was estimated as 2 : 1, which was in agreement with the results of high resolution mass spectrum and Job's plot. In addition, the binding constant was evaluated as 6.77 × 10² M^-1 using a Benesi-Hildebrand plot. Finally, the obtained L1-based indicator paper showed significant fluorescence response to Cu²⁺ aqueous solution. This TPE-modified strategy improves the detection capability of curcumin probe in aqueous solution and provides a feasible way to obtain other probes with ACQ characteristics.

SUBMITTER: Lin Y

PROVIDER: S-EPMC9170379 | biostudies-literature |

REPOSITORIES: biostudies-literature

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