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Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management.


ABSTRACT: Chronic kidney disease (CKD) is associated with significant morbidity and mortality worldwide. In recent years, our understanding of genetic causes of CKD has expanded significantly with several renal conditions having been identified. This review discusses the current landscape of genetic kidney disease and their potential treatment options. This review will focus on cystic kidney disease, glomerular disease with genetic associations, congenital anomalies of kidneys and urinary tract (CAKUT), autosomal dominant-tubulointerstitial kidney disease (ADTKD), inherited nephrolithiasis and nephrocalcinosis.

SUBMITTER: Sawaf H 

PROVIDER: S-EPMC9831004 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management.

Sawaf Hanny H   Gudura Tariku T TT   Dorobisz Sylvester S   Sandy Dianne D   Wang Xiangling X   Bobart Shane A SA  

International journal of nephrology and renovascular disease 20230105


Chronic kidney disease (CKD) is associated with significant morbidity and mortality worldwide. In recent years, our understanding of genetic causes of CKD has expanded significantly with several renal conditions having been identified. This review discusses the current landscape of genetic kidney disease and their potential treatment options. This review will focus on cystic kidney disease, glomerular disease with genetic associations, congenital anomalies of kidneys and urinary tract (CAKUT), a  ...[more]

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