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Yeast postcatalytic spliceosome, two cryoEM data sets at different magnifications

ABSTRACT:

SUBMITTER: Max Wilkinson

PROVIDER: EMPIAR-10298 | biostudies-other |

REPOSITORIES: biostudies-other

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Methods for merging data sets in electron cryo-microscopy.

Wilkinson Max E ME Kumar Ananthanarayanan A Casañal Ana A

Acta crystallographica. Section D, Structural biology 20190823 Pt 9

Recent developments have resulted in electron cryo-microscopy (cryo-EM) becoming a useful tool for the structure determination of biological macromolecules. For samples containing inherent flexibility, heterogeneity or preferred orientation, the collection of extensive cryo-EM data using several conditions and microscopes is often required. In such a scenario, merging cryo-EM data sets is advantageous because it allows improved three-dimensional reconstructions to be obtained. Since data sets ar ...[more]

PMID: 31478901

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