Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC2600837 | biostudies-other | 2008 Feb
REPOSITORIES: biostudies-other
Li Jie J Yin Chunyue C Okamoto Hiroaki H Mushlin Harry H Balgley Brian M BM Lee Cheng S CS Yuan Kristy K Ikejiri Barbara B Glasker Sven S Vortmeyer Alexander O AO Oldfield Edward H EH Weil Robert J RJ Zhuang Zhengping Z
Neuro-oncology 20080108 1
Dynamic changes in the expression of multiple genes appear to be common features that distinguish transformed cells from their normal counterparts. We compared the proteomic profiles of four glioblastoma multiforme (GBM) tissue samples and four normal brain cortex samples to examine the molecular basis of gliomagenesis. Trypsin-digested protein samples were separated by capillary isoelectric focusing with nano-reversed-phase liquid chromatography and were profiled by mass spectrometric sequencin ...[more]