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A versatile route to the tulearin class of macrolactones: synthesis of a stereoisomer of tulearin A.

ABSTRACT: A versatile synthetic approach to the tulearin class of macrolactones has been developed and deployed to make a stereoisomer of tulearin A. The knowledge gained about structure and synthesis will expedite the assignment of the stereostructure of this new anticancer agent.

SUBMITTER: Mandel AL

PROVIDER: S-EPMC2736336 | biostudies-other | 2009 Aug

REPOSITORIES: biostudies-other

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A versatile route to the tulearin class of macrolactones: synthesis of a stereoisomer of tulearin A.

Mandel Alexander L AL Bellosta Véronique V Curran Dennis P DP Cossy Janine J

Organic letters 20090801 15

A versatile synthetic approach to the tulearin class of macrolactones has been developed and deployed to make a stereoisomer of tulearin A. The knowledge gained about structure and synthesis will expedite the assignment of the stereostructure of this new anticancer agent. ...[more]

PMID: 19555117

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