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A fast ruthenium polypyridine cage complex photoreleases glutamate with visible or IR light in one and two photon regimes.

ABSTRACT: We introduce a new caged glutamate, based in a ruthenium bipyridyl core, that undergoes heterolytic cleavage after irradiation with visible light with wavelengths up to 532nm, yielding free glutamate in less than 50ns. Glutamate photorelease occurs also efficiently following two-photon (2P) excitation at 800nm, and has a functional cross section of 0.14GM.

SUBMITTER: Salierno M

PROVIDER: S-EPMC2835317 | biostudies-other | 2010 Apr

REPOSITORIES: biostudies-other

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A fast ruthenium polypyridine cage complex photoreleases glutamate with visible or IR light in one and two photon regimes.

Salierno Marcelo M Marceca Ernesto E Peterka Darcy S DS Yuste Rafael R Etchenique Roberto R

Journal of inorganic biochemistry 20091211 4

We introduce a new caged glutamate, based in a ruthenium bipyridyl core, that undergoes heterolytic cleavage after irradiation with visible light with wavelengths up to 532nm, yielding free glutamate in less than 50ns. Glutamate photorelease occurs also efficiently following two-photon (2P) excitation at 800nm, and has a functional cross section of 0.14GM. ...[more]

PMID: 20060592

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