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Ion bipolar junction transistors.

ABSTRACT: Dynamic control of chemical microenvironments is essential for continued development in numerous fields of life sciences. Such control could be achieved with active chemical circuits for delivery of ions and biomolecules. As the basis for such circuitry, we report a solid-state ion bipolar junction transistor (IBJT) based on conducting polymers and thin films of anion- and cation-selective membranes. The IBJT is the ionic analogue to the conventional semiconductor BJT and is manufactured using standard microfabrication techniques. Transistor characteristics along with a model describing the principle of operation, in which an anionic base current amplifies a cationic collector current, are presented. By employing the IBJT as a bioelectronic circuit element for delivery of the neurotransmitter acetylcholine, its efficacy in modulating neuronal cell signaling is demonstrated.

SUBMITTER: Tybrandt K

PROVIDER: S-EPMC2890459 | biostudies-other | 2010 Jun

REPOSITORIES: biostudies-other

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Ion bipolar junction transistors.

Tybrandt Klas K Larsson Karin C KC Richter-Dahlfors Agneta A Berggren Magnus M

Proceedings of the National Academy of Sciences of the United States of America 20100517 22

Dynamic control of chemical microenvironments is essential for continued development in numerous fields of life sciences. Such control could be achieved with active chemical circuits for delivery of ions and biomolecules. As the basis for such circuitry, we report a solid-state ion bipolar junction transistor (IBJT) based on conducting polymers and thin films of anion- and cation-selective membranes. The IBJT is the ionic analogue to the conventional semiconductor BJT and is manufactured using s ...[more]

PMID: 20479274

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