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(11R,11aS)-11-Hydr-oxy-1,5,11,11a-tetra-hydro-1-benzothieno[2,3-f]indolizin-3(2H)-one.

ABSTRACT: The absolute configuration of the title compound, C(14)H(13)NO(2)S, was assigned from the synthesis and confirmed by the structure determination. The central six-membered ring of the indolizine system adopts an envelope conformation, the greatest deviation from the mean plane of the ring being 0.459?(2)?Å for the N atom. The benzothieno system is planar [mean deviation = 0.009?(2)?Å]. In the crystal structure, mol-ecules form chains parallel to the b axis via inter-molecular O-H?O hydrogen bonds.

SUBMITTER: Svorc L

PROVIDER: S-EPMC2961476 | biostudies-other | 2008

REPOSITORIES: biostudies-other

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(11R,11aS)-11-Hydr-oxy-1,5,11,11a-tetra-hydro-1-benzothieno[2,3-f]indolizin-3(2H)-one.

Svorc Lubomír L Vrábel Viktor V Kožíšek Jozef J Marchalín Stefan S Safář Peter P

Acta crystallographica. Section E, Structure reports online 20080530 Pt 6

The absolute configuration of the title compound, C(14)H(13)NO(2)S, was assigned from the synthesis and confirmed by the structure determination. The central six-membered ring of the indolizine system adopts an envelope conformation, the greatest deviation from the mean plane of the ring being 0.459 (2) Å for the N atom. The benzothieno system is planar [mean deviation = 0.009 (2) Å]. In the crystal structure, mol-ecules form chains parallel to the b axis via inter-molecular O-H⋯O hydrogen bonds ...[more]

PMID: 21202672

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