Ontology highlight
ABSTRACT:
SUBMITTER: Biteau B
PROVIDER: S-EPMC3042864 | biostudies-other | 2011 Mar
REPOSITORIES: biostudies-other
Development (Cambridge, England) 20110209 6
Precise control of somatic stem cell proliferation is crucial to ensure maintenance of tissue homeostasis in high-turnover tissues. In Drosophila, intestinal stem cells (ISCs) are essential for homeostatic turnover of the intestinal epithelium and ensure epithelial regeneration after tissue damage. To accommodate these functions, ISC proliferation is regulated dynamically by various growth factors and stress signaling pathways. How these signals are integrated is poorly understood. Here, we show ...[more]