Ontology highlight
ABSTRACT:
SUBMITTER: Cho HS
PROVIDER: S-EPMC3394190 | biostudies-other | 2012 Jun
REPOSITORIES: biostudies-other
Cho Hyun-Soo HS Hayami Shinya S Toyokawa Gouji G Maejima Kazuhiro K Yamane Yuka Y Suzuki Takehiro T Dohmae Naoshi N Kogure Masaharu M Kang Daechun D Neal David E DE Ponder Bruce A J BA Yamaue Hiroki H Nakamura Yusuke Y Hamamoto Ryuji R
Neoplasia (New York, N.Y.) 20120601 6
It is well known that RB functions are regulated by posttranslational modifications such as phosphorylation and acetylation, but the significance of lysine methylation on RB has not been fully elucidated. Our expression analysis of SMYD2 by quantitative real-time polymerase chain reaction showed that expression levels of SMYD2 are significantly elevated in human bladder carcinomas compared with nonneoplastic bladder tissues (P < .0001), and its expression levels in tumor tissues were much higher ...[more]