Ontology highlight
ABSTRACT:
SUBMITTER: Munemitsu S
PROVIDER: S-EPMC361395 | biostudies-other | 1990 Nov
REPOSITORIES: biostudies-other
Munemitsu S S Innis M A MA Clark R R McCormick F F Ullrich A A Polakis P P
Molecular and cellular biology 19901101 11
G25K is a low-molecular-mass GTP-binding protein with a broad distribution in mammalian tissues. A cDNA clone was isolated by using oligonucleotides corresponding to the partial amino acid sequence of purified human G25K. The cDNA encodes an 191-amino-acid polypeptide containing GTP-binding consensus sequences and a putative farnesylation site at the C terminus. The sequence exhibits 50 and 70% identities to the mammalian rho and rac proteins, respectively, and an 80% identity to the Saccharomyc ...[more]