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Characterization of single 1.8-nm Au nanoparticle attachments on AFM tips for single sub-4-nm object pickup.

ABSTRACT: This paper presents a novel method for the attachment of a 1.8-nm Au nanoparticle (Au-NP) to the tip of an atomic force microscopy (AFM) probe through the application of a current-limited bias voltage. The resulting probe is capable of picking up individual objects at the sub-4-nm scale. We also discuss the mechanisms involved in the attachment of the Au-NP to the very apex of an AFM probe tip. The Au-NP-modified AFM tips were used to pick up individual 4-nm quantum dots (QDs) using a chemically functionalized method. Single QD blinking was reduced considerably on the Au-NP-modified AFM tip. The resulting AFM tips present an excellent platform for the manipulation of single protein molecules in the study of single protein-protein interactions.

SUBMITTER: Cheng HW

PROVIDER: S-EPMC3835868 | biostudies-other | 2013

REPOSITORIES: biostudies-other

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Characterization of single 1.8-nm Au nanoparticle attachments on AFM tips for single sub-4-nm object pickup.

Cheng Hui-Wen HW Chang Yuan-Chih YC Tang Song-Nien SN Yuan Chi-Tsu CT Tang Jau J Tseng Fan-Gang FG

Nanoscale research letters 20131115 1

This paper presents a novel method for the attachment of a 1.8-nm Au nanoparticle (Au-NP) to the tip of an atomic force microscopy (AFM) probe through the application of a current-limited bias voltage. The resulting probe is capable of picking up individual objects at the sub-4-nm scale. We also discuss the mechanisms involved in the attachment of the Au-NP to the very apex of an AFM probe tip. The Au-NP-modified AFM tips were used to pick up individual 4-nm quantum dots (QDs) using a chemically ...[more]

PMID: 24237663

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