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Recyclable polystyrene-supported siloxane-transfer agent for palladium-catalyzed cross-coupling reactions.

ABSTRACT: The rational design, synthesis, and validation of a significantly improved insoluble polymer-supported siloxane-transfer agent has been achieved that permits efficient palladium-catalyzed cross-coupling reactions. The cross-linked polystyrene support facilitates product purification with excellent siloxane recycling. Drawbacks of a previous polymer-supported siloxane-transfer agent, relating to reaction efficiency and polymer stability after repeated cycles, have been addressed.

SUBMITTER: Nguyen MH

PROVIDER: S-EPMC3993864 | biostudies-other | 2014 Apr

REPOSITORIES: biostudies-other

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Recyclable polystyrene-supported siloxane-transfer agent for palladium-catalyzed cross-coupling reactions.

Nguyen Minh H MH Smith Amos B AB

Organic letters 20140324 7

The rational design, synthesis, and validation of a significantly improved insoluble polymer-supported siloxane-transfer agent has been achieved that permits efficient palladium-catalyzed cross-coupling reactions. The cross-linked polystyrene support facilitates product purification with excellent siloxane recycling. Drawbacks of a previous polymer-supported siloxane-transfer agent, relating to reaction efficiency and polymer stability after repeated cycles, have been addressed. ...[more]

PMID: 24661113

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