Ontology highlight
ABSTRACT:
SUBMITTER: Ivanova EV
PROVIDER: S-EPMC4883394 | biostudies-other | 2016 May
REPOSITORIES: biostudies-other
Sensors (Basel, Switzerland) 20160516 5
FRET biosensors have become a routine tool for investigating mechanisms and components of cell signaling. Strategies for improving them for particular applications are continuously sought. One important aspect to consider when designing FRET probes is the dynamic distribution and propagation of signals within living cells. We have addressed this issue by directly comparing an anchored (taFS) to a non-anchored (naFS) cleavable FRET sensor. We chose a microtubule-associated protein tau as an ancho ...[more]