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Oligomeric catechins: an enabling synthetic strategy by orthogonal activation and C(8) protection.


ABSTRACT: Controlled formation of oligomeric catechins has become possible by an orthogonal synthetic strategy. Bromo-capping of the C(8) position of the flavan skeleton enabled the equimolar coupling of electrophilic and nucleophilic catechin derivatives, enabling an efficient synthetic strategy to complex catechin oligomers.

SUBMITTER: Ohmori K 

PROVIDER: S-EPMC514424 | biostudies-other | 2004 Aug

REPOSITORIES: biostudies-other

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