Ontology highlight
ABSTRACT:
SUBMITTER: Lequieu J
PROVIDER: S-EPMC5676884 | biostudies-other | 2017 Oct
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 20171018 44
Nucleosomes represent the basic building block of chromatin and provide an important mechanism by which cellular processes are controlled. The locations of nucleosomes across the genome are not random but instead depend on both the underlying DNA sequence and the dynamic action of other proteins within the nucleus. These processes are central to cellular function, and the molecular details of the interplay between DNA sequence and nucleosome dynamics remain poorly understood. In this work, we in ...[more]