Ontology highlight
ABSTRACT:
SUBMITTER: Weber-Ouellette A
PROVIDER: S-EPMC6088263 | biostudies-other | 2018 Jul
REPOSITORIES: biostudies-other
Weber-Ouellette Anne A Busby Mélanie M Plante Isabelle I
Future science OA 20180628 7
The epithelium's functional unit is the bilayered acinus, made of a layer of luminal cells, surrounded by a layer of basal cells mainly composed of myoepithelial cells.<h4>Aim</h4>The aim of this study was to develop a reproducible and manipulable 3D co-culture model of the bilayered acinus <i>in vitro</i> to study the interactions between the two layers.<h4>Materials & methods</h4>Two different combinations of cell lines were co-cultured in Matrigel: SCp2 and SCg6 mice cells, or MCF-12A and Hs ...[more]