Ontology highlight
ABSTRACT:
SUBMITTER: Peng JL
PROVIDER: S-EPMC6274087 | biostudies-other | 2016 Jan
REPOSITORIES: biostudies-other
Peng Jun-Lin JL Wang Jun J Kong Fan-Dong FD Liu Zi-Qi ZQ Wang Pei P Gai Cui-Juan CJ Jiang Bei B Mei Wen-Li WL Dai Hao-Fu HF
Molecules (Basel, Switzerland) 20160105 1
Phytochemical investigation on the stems of C. tabularis led to the isolation of five new phragmalin-type limonoids and six known ones. The structures of the new compounds 1-5, named chukbularisins A-E, were elucidated by spectroscopic techniques (IR, HRESIMS, 1D and 2D NMR) and comparisons with published data. All the compounds were evaluated for in vitro α-glucosidase inhibitory activity. Compounds 2, 3, 4, 5, and 8 exhibited inhibitory activity against α-glucosidase with IC50 values of 0.06 ± ...[more]