Ontology highlight
ABSTRACT:
SUBMITTER: Chen H
PROVIDER: S-EPMC6478907 | biostudies-other | 2019 Apr
REPOSITORIES: biostudies-other
Nature communications 20190423 1
Single-cell transcriptomic assays have enabled the de novo reconstruction of lineage differentiation trajectories, along with the characterization of cellular heterogeneity and state transitions. Several methods have been developed for reconstructing developmental trajectories from single-cell transcriptomic data, but efforts on analyzing single-cell epigenomic data and on trajectory visualization remain limited. Here we present STREAM, an interactive pipeline capable of disentangling and visual ...[more]