Sotalol: Cardiovascular Effects of sotalol in Conscious, Telemetered Beagle Dogs

ABSTRACT: n=3 chronically-instrumented conscious male Beagle dogs, dosed with Sotalol at 20 mg/kg, p.o. No PK phase. Parameters: haemodynamic parameters (SAP, DAP, MAP, HR) and ECG (RR, PR, QRS, QT, QTcB and QTcVdW intervals), body temperature. All parameters were analysed before treatment: -0.75, -0.5 and -0.25 hours and after treatment: 0.5, 0.75, 1, 1.5, 2, 3, 4, 6, 8, 12 and 24 hours.

ORGANISM(S): Beagle dogs

SUBMITTER:  

PROVIDER: S-TQST63 | biostudies-other |

REPOSITORIES: biostudies-other